Thank you for visiting our website. Our group, which spans Biomaterials, Tissue Engineering and Bioengineering is very interdisciplinary and focused on translational research – an important theme of the University of Sheffield. Our research spans blue skies research into new techniques, including imaging, working with colleagues in evaluating new chemicals, novel tissue engineering of scaffolds, development of tissue engineered models, right through to taking biomaterials and tissue engineered products to clinical translation and commercialisation.
Several members of our group are engaged in international collaborations with India and Pakistan to develop biomaterials and tissue engineering solutions to translate through to affordable healthcare solutions.
Within the University of Sheffield members of the group work with colleagues in Chemistry, developing new fluorescent agents, new antimicrobial peptides and hydrogels and with colleagues in Medicine and Dentistry and Biomedical Sciences. Commonly PhD students will find themselves working between two departments gaining valuable experience in interdisciplinary research in a supportive atmosphere.
Dr Naside Mangir, a clinical urologist who has just completed her PhD in Prof MacNeil’s group, looked back more than 50 years to try to explain why a material, polypropylene, has led to severe complications when it has been used in woman to support prolapsed pelvic organs. Polypropylene has been used successfully in the treatment … Continue reading “Developing synthetic materials for treatment of stress urinary incontinence and pelvic organ prolapse in women: lessons learnt from the mesh experience”MORE INFORMATION
Meshes used for urinary incontinence and pelvic repair must endure decades of distension caused by everyday activities such as laughing or sneezing. Testing mechanical properties is vital during material selection for implantation in the pelvic floor. In this study, Prof Sheila MacNeil´s group describe a simple methodology to test the fatigue behaviour of several pelvic … Continue reading “Accelerated fatigue testing for assessing materials for pelvic floor repair”MORE INFORMATION
Past consensus in the silk community has been that spinning silk is hard – in particular, that it is a matter of how hard. Others have suggested that spinning silk is simply a matter of speed, but our recent work tells us that we need to throw time into the mix. Taking inspiration from the Olympic … Continue reading “Spinning silk needs Work!”MORE INFORMATION
There is an urgent need to develop better materials that provide anatomical support to the pelvic floor without compromising function. Our aim was to assess outcomes, after simulated vaginal prolapse repair in a sheep model, using novel materials with a better design for pelvic floor repair, and therefore, with potential to reduce implant-related complications and … Continue reading “Electrospun and polypropylene meshes assessed in the sheep model for pelvic floor repair”MORE INFORMATION
Sheila MacNeil was awarded the Chapman medal for medical biomaterials from the Institute of Materials Minerals and Mining on 3 July 2018. For full details of this please see www.iom3.org/iom3-awards-2018 Sheila accepted this award on behalf of her group and the great clinical collaborators with whom she has worked with over the years. She was presented the award … Continue reading “Professor Sheila MacNeil wins the Chapman medal for Medical Biomaterials”MORE INFORMATION