Thank you for visiting our website. Our group, which spans Biomaterials, Tissue Engineering and Bioengineering is very interdisciplinary and focused on translational research – an important theme of the University of Sheffield. Our research spans blue skies research into new techniques, including imaging, working with colleagues in evaluating new chemicals, novel tissue engineering of scaffolds, development of tissue engineered models, right through to taking biomaterials and tissue engineered products to clinical translation and commercialisation.
Several members of our group are engaged in international collaborations with India and Pakistan to develop biomaterials and tissue engineering solutions to translate through to affordable healthcare solutions.
Within the University of Sheffield members of the group work with colleagues in Chemistry, developing new fluorescent agents, new antimicrobial peptides and hydrogels and with colleagues in Medicine and Dentistry and Biomedical Sciences. Commonly PhD students will find themselves working between two departments gaining valuable experience in interdisciplinary research in a supportive atmosphere.
Angiogenesis assays are essential for studying aspects of neovascularisation and angiogenesis and investigating drugs that stimulate or inhibit angiogenesis. To date, there are several in vitro and in vivo angiogenesis assays that are used for studying different aspects of angiogenesis. Although in vivo assays are the most representative of native angiogenesis, they raise ethical questions, … Continue reading “Bioengineering vascular networks to study angiogenesis and vascularisation of physiologically relevant tissue models in vitro”MORE INFORMATION
Boosting the Osteogenic and Angiogenic Performance of Multiscale Porous Polycaprolactone Scaffolds by In Vitro Generated Extracellular Matrix Decoration
Tissue engineering (TE)-based bone grafts are favourable alternatives to autografts and allografts. Both biochemical properties and the architectural features of TE scaffolds are crucial in their design process. Synthetic polymers are attractive biomaterials to be used in the manufacturing of TE scaffolds, due to various advantages; such as being relatively inexpensive, enabling precise reproducibility, possessing … Continue reading “Boosting the Osteogenic and Angiogenic Performance of Multiscale Porous Polycaprolactone Scaffolds by In Vitro Generated Extracellular Matrix Decoration”MORE INFORMATION
This year’s Annual Meeting of the White Rose Biomaterials and Tissue Engineering Group (BiTEG) was held on the 16th December at the University of York. Postgraduate Researchers, Betül Aldemir Dikici and Serkan Dikici, from Sheffield Biomaterials and Bioengineering group at the Kroto Research Institute shared their research BiTEG 2019 with poster and oral presentations. Betül … Continue reading “Best poster and presentation awards for biomaterials students at the Annual BiTEG Meeting in York”MORE INFORMATION
Development of a novel in vitro 3D dynamic model that enables researchers to study angiogenesis under physiologically more relevant conditions
Betül Aldemir and Serkan Dikici, bioengineers who are currently doing their PhDs under Dr Frederik Claeyssens and Prof Sheila MacNeil’ supervision, respectively, have recently joined Balcells Lab located at Institute for Medical Engineering and Science, MIT, Boston, USA for 6 months to developed a novel in vitro 3D dynamic model that enables researchers to study … Continue reading “Development of a novel in vitro 3D dynamic model that enables researchers to study angiogenesis under physiologically more relevant conditions”MORE INFORMATION
Developing synthetic materials for treatment of stress urinary incontinence and pelvic organ prolapse in women: lessons learnt from the mesh experience
Dr Naside Mangir, a clinical urologist who has just completed her PhD in Prof MacNeil’s group, looked back more than 50 years to try to explain why a material, polypropylene, has led to severe complications when it has been used in woman to support prolapsed pelvic organs. Polypropylene has been used successfully in the treatment … Continue reading “Developing synthetic materials for treatment of stress urinary incontinence and pelvic organ prolapse in women: lessons learnt from the mesh experience”MORE INFORMATION