Electrospray filaments forming a tri-layer scaffold for tissue engineering.
Actin staining of corneal cell outgrowth from limbal explants on fibrin coated scaffold after 2 week
Tracing paths taken by nerve fibres
Tissue engineered skin being used for contracture release
Cells growing on scaffold

New scaffolds show promise for tissue engineering (above)

Electrospray scaffolds

New scaffolds show promise for tissue engineering
More about Electrospray scaffolds

Electrospun scaffolds for tissue engineering.

Actin staining of corneal cell outgrowth (above)

Corneal Cell Outgrowth

Actin staining of corneal cell outgrowth from limbal explants on fibrin coated scaffolds after 2 weeks
More about Corneal Cell Outgrowth

Actin staining of corneal cell outgrowth

Tracing paths taken by nerve fibres (above)

Nerve Fibres

Tracing paths taken by nerve fibres
More about Nerve Fibres

Paths taken by nerve fibres

Tissue engineered skin being used for contracture release (above)

Tissue engineered skin

Tissue engineered skin being used for contraction release in patients suffering from skin graft contractures.
More about Tissue engineered skin

Tissue engineered skin for contracture release

Tissue Engineering for Repair of Pelvic Floor (above)

Tissue Engineering

Tissue engineering for repair of pelvic floor. Image taken by Dr Anthony Bullock.
More about Tissue Engineering

Tissue engineering for repair of pelvic floor. Image taken by Dr Anthony Bullock.

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Welcome

Thank you for visiting our website.  Our group, which spans Biomaterials, Tissue Engineering and Bioengineering is very interdisciplinary and focused on translational research – an important theme of the University of Sheffield.  Our research spans blue skies research into new techniques, including imaging, working with colleagues in evaluating new chemicals, novel tissue engineering of scaffolds, development of tissue engineered models, right through to taking biomaterials and tissue engineered products to clinical translation and commercialisation.

Several members of our group are engaged in international collaborations with India and Pakistan to develop biomaterials and tissue engineering solutions to translate through to affordable healthcare solutions.

Within the University of Sheffield members of the group work with colleagues in Chemistry, developing new fluorescent agents, new antimicrobial peptides and hydrogels and with colleagues in Medicine and Dentistry and Biomedical Sciences. Commonly PhD students will find themselves working between two departments gaining valuable experience in interdisciplinary research in a supportive atmosphere.

For more detail on our activities please look under Research Themes of Tissue Engineering, Biomaterials Characterisation, Biomaterials Production and Clinical Translation.

 

Latest news

Accelerated fatigue testing for assessing materials for pelvic floor repair

Meshes used for urinary incontinence and pelvic repair must endure decades of distension caused by everyday activities such as laughing or sneezing. Testing mechanical properties is vital during material selection for implantation in the pelvic floor. In this study, Prof Sheila MacNeil´s group describe a simple methodology to test the fatigue behaviour of several pelvic … Continue reading “Accelerated fatigue testing for assessing materials for pelvic floor repair”

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Spinning silk needs Work!

Past consensus in the silk community has been that spinning silk is hard – in particular, that it is a matter of how hard. Others have suggested that spinning silk is simply a matter of speed, but our recent work tells us that we need to throw time into the mix. Taking inspiration from the Olympic … Continue reading “Spinning silk needs Work!”

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Electrospun and polypropylene meshes assessed in the sheep model for pelvic floor repair

There is an urgent need to develop better materials that provide anatomical support to the pelvic floor without compromising function. Our aim was to assess outcomes, after simulated vaginal prolapse repair in a sheep model, using novel materials with a better design for pelvic floor repair, and therefore, with potential to reduce implant-related complications and … Continue reading “Electrospun and polypropylene meshes assessed in the sheep model for pelvic floor repair”

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Professor Sheila MacNeil wins the Chapman medal for Medical Biomaterials

Sheila MacNeil was awarded the Chapman medal for medical biomaterials from the Institute of Materials Minerals and Mining on 3 July 2018. For full details of this please see www.iom3.org/iom3-awards-2018 Sheila accepted this award on behalf of her group and the great clinical collaborators with whom she has worked with over the years. She was presented the award … Continue reading “Professor Sheila MacNeil wins the Chapman medal for Medical Biomaterials”

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Porous microspheres support mesenchymal progenitor cell ingrowth and stimulate angiogenesis

We all know how important communication is in science which is why ShefBioMat researcher Dr Tom Paterson decided to try something a little different. He produced this eye catching infographic to accompany a recently published paper entitled “Porous microspheres support mesenchymal progenitor cell ingrowth and stimulate angiogenesis”. The aim was to improve the impact of … Continue reading “Porous microspheres support mesenchymal progenitor cell ingrowth and stimulate angiogenesis”

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