Electrospray filaments forming a tri-layer scaffold for tissue engineering.
Actin staining of corneal cell outgrowth from limbal explants on fibrin coated scaffold after 2 week
Tracing paths taken by nerve fibres
Tissue engineered skin being used for contracture release
Cells growing on scaffold

New scaffolds show promise for tissue engineering (above)

Electrospray scaffolds

New scaffolds show promise for tissue engineering
More about Electrospray scaffolds

Electrospun scaffolds for tissue engineering.

Actin staining of corneal cell outgrowth (above)

Corneal Cell Outgrowth

Actin staining of corneal cell outgrowth from limbal explants on fibrin coated scaffolds after 2 weeks
More about Corneal Cell Outgrowth

Actin staining of corneal cell outgrowth

Tracing paths taken by nerve fibres (above)

Nerve Fibres

Tracing paths taken by nerve fibres
More about Nerve Fibres

Paths taken by nerve fibres

Tissue engineered skin being used for contracture release (above)

Tissue engineered skin

Tissue engineered skin being used for contraction release in patients suffering from skin graft contractures.
More about Tissue engineered skin

Tissue engineered skin for contracture release

Tissue Engineering for Repair of Pelvic Floor (above)

Tissue Engineering

Tissue engineering for repair of pelvic floor. Image taken by Dr Anthony Bullock.
More about Tissue Engineering

Tissue engineering for repair of pelvic floor. Image taken by Dr Anthony Bullock.

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Welcome

Thank you for visiting our website.  Our group, which spans Biomaterials, Tissue Engineering and Bioengineering is very interdisciplinary and focused on translational research – an important theme of the University of Sheffield.  Our research spans blue skies research into new techniques, including imaging, working with colleagues in evaluating new chemicals, novel tissue engineering of scaffolds, development of tissue engineered models, right through to taking biomaterials and tissue engineered products to clinical translation and commercialisation.

Several members of our group are engaged in international collaborations with India and Pakistan to develop biomaterials and tissue engineering solutions to translate through to affordable healthcare solutions.

Within the University of Sheffield members of the group work with colleagues in Chemistry, developing new fluorescent agents, new antimicrobial peptides and hydrogels and with colleagues in Medicine and Dentistry and Biomedical Sciences. Commonly PhD students will find themselves working between two departments gaining valuable experience in interdisciplinary research in a supportive atmosphere.

For more detail on our activities please look under Research Themes of Tissue Engineering, Biomaterials Characterisation, Biomaterials Production and Clinical Translation.

 

Latest news

Design and Evaluation of an Osteogenesis-on-a-Chip Microfluidic Device Incorporating 3D Cell Culture

University of Sheffield engineers have developed a technology that could change the way we test new medical treatments to repair human organs and bone tissue. The new technology uses mini scaffolding 3D structures capable of growing bone-on-a-chip. The development could reduce the number of animal models used in research. The researchers are part of the … Continue reading “Design and Evaluation of an Osteogenesis-on-a-Chip Microfluidic Device Incorporating 3D Cell Culture”

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Basic Principles of Emulsion Templating and Its Use as an Emerging Manufacturing Method of Tissue Engineering Scaffolds

Tissue engineering (TE) aims to regenerate critical size defects, which cannot heal naturally, by using highly porous matrices called TE scaffolds made of biocompatible and biodegradable materials. There are various manufacturing techniques commonly used to fabricate TE scaffolds. However, in most cases, they do not provide materials with a highly interconnected pore design. Thus, emulsion … Continue reading “Basic Principles of Emulsion Templating and Its Use as an Emerging Manufacturing Method of Tissue Engineering Scaffolds”

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Bioengineering vascular networks to study angiogenesis and vascularisation of physiologically relevant tissue models in vitro

Angiogenesis assays are essential for studying aspects of neovascularisation and angiogenesis and investigating drugs that stimulate or inhibit angiogenesis. To date, there are several in vitro and in vivo angiogenesis assays that are used for studying different aspects of angiogenesis. Although in vivo assays are the most representative of native angiogenesis, they raise ethical questions, … Continue reading “Bioengineering vascular networks to study angiogenesis and vascularisation of physiologically relevant tissue models in vitro”

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Boosting the Osteogenic and Angiogenic Performance of Multiscale Porous Polycaprolactone Scaffolds by In Vitro Generated Extracellular Matrix Decoration

Tissue engineering (TE)-based bone grafts are favourable alternatives to autografts and allografts. Both biochemical properties and the architectural features of TE scaffolds are crucial in their design process. Synthetic polymers are attractive biomaterials to be used in the manufacturing of TE scaffolds, due to various advantages; such as being relatively inexpensive, enabling precise reproducibility, possessing … Continue reading “Boosting the Osteogenic and Angiogenic Performance of Multiscale Porous Polycaprolactone Scaffolds by In Vitro Generated Extracellular Matrix Decoration”

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Best poster and presentation awards for biomaterials students at the Annual BiTEG Meeting in York

This year’s Annual Meeting of the White Rose Biomaterials and Tissue Engineering Group (BiTEG) was held on the 16th December at the University of York. Postgraduate Researchers, Betül Aldemir Dikici and Serkan Dikici, from Sheffield Biomaterials and Bioengineering group at the Kroto Research Institute shared their research BiTEG 2019 with poster and oral presentations. Betül … Continue reading “Best poster and presentation awards for biomaterials students at the Annual BiTEG Meeting in York”

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